Back to Search
Start Over
Risk Factors for Nephrolithiasis in Adults with Short Bowel Syndrome.
- Source :
-
Annals of Nutrition & Metabolism . Sep2019, Vol. 75 Issue 1, p47-54. 8p. 1 Black and White Photograph, 4 Charts. - Publication Year :
- 2019
-
Abstract
- Introduction: Patients with short bowel syndrome (SBS) commonly develop nephrolithiasis. However, the risk factors for nephrolithiasis in patients with SBS remain unclarified. The present study aimed to identify the risk factors for nephrolithiasis in adults with SBS. Methods: All eligible adults diagnosed with SBS and admitted to a tertiary referral center from December 2008 to 2018 were retrospectively identified from a prospectively maintained database. Patients' demographic and clinical characteristics were analyzed using univariate and multivariate analyses to identify the risk factors for nephrolithiasis. Results: Of 231 adults with SBS, 42 (18.2%) developed nephrolithiasis. The mean age was 46.4 ± 17.8 years, the mean body mass index was 18.2 ± 3.8 kg/m2, and median duration of SBS was 11 months (range 2–324 months). Multivariate binary logistic regression analysis revealed that the independent risk factors for nephrolithiasis in adults with SBS were jejuno-ileal anastomosis and colon-in-continuity (OR 4.335; 95% CI 1.175–16.002; p = 0.028), prolonged duration of SBS (OR 1.008; 95% CI 1.002–1.014; p = 0.010), and increased serum creatinine concentration (OR 1.005; 95% CI 1.001–1.009; p = 0.012). Conclusions: Nephrolithiasis is common in adults with SBS. As nephrolithiasis can have adverse clinical consequences, patients with SBS should be closely monitored, and prophylactic interventions should be considered. [ABSTRACT FROM AUTHOR]
- Subjects :
- *URINARY calculi
*COLON diseases
*CONFIDENCE intervals
*CREATININE
*HOSPITAL admission & discharge
*MULTIVARIATE analysis
*PATIENTS
*RISK assessment
*STATISTICS
*MULTIPLE regression analysis
*SYMPTOMS
*BODY mass index
*RETROSPECTIVE studies
*DISEASE duration
*SURGICAL anastomosis
*SHORT bowel syndrome
*TERTIARY care
*ODDS ratio
*DISEASE complications
*DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 02506807
- Volume :
- 75
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Annals of Nutrition & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 138733804
- Full Text :
- https://doi.org/10.1159/000502329