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利伐沙班和达比加群酯在高龄非瓣膜性房颤患者中的 有效性及安全性观察
- Source :
-
Progress in Modern Biomedicine . Jul2019, Vol. 19 Issue 13, p2486-2489. 4p. - Publication Year :
- 2019
-
Abstract
- Objective: To investigate the efficacy and safety of Rivaroxaban and Dabigatran in elderly patients with non-valvular AF. Methods: A retrospective analysis of 202 elderly patients(Rivaroxaban = 116, Dabigatran = 86) with non-valvular atrial fibrillation hospitalized in our department of Cardiology from September 2016 to March 2018 was performed. The average follow-up period was 9 months. Comparation of the basic clinical data, the efficacy end point and clinical relevant bleeding between the two groups were done.Results: The efficacy end point occurred in 4 patients in the Rivaroxaban group and the Dabigatran group respectively. There was no significant difference in efficacy between the two groups(P > 0.05). Ischemic stroke was the most common thromboembolic events(4/8).Clinical relevant bleeding occurred in 15 patients in the Rivaroxaban group and 10 in the Dabigatran group. There was no significant difference in safety between the two groups(P > 0.05). Gastrointestinal bleeding was the most common bleeding events(7/25).Conclusions: The efficacy and safety of Rivaroxaban and Dabigartran in elderly patients with non-valvular AF are similar. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ATRIAL fibrillation
*OLDER patients
*RIVAROXABAN
*HEMORRHAGE
*CARDIOLOGY
Subjects
Details
- Language :
- Chinese
- ISSN :
- 16736273
- Volume :
- 19
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Progress in Modern Biomedicine
- Publication Type :
- Academic Journal
- Accession number :
- 138712884
- Full Text :
- https://doi.org/10.13241/j.cnki.pmb.2019.13.019