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Associations of Subjective Memory Complaints and Simple Memory Task Scores With Future Dementia in the Primary Care Setting.
- Source :
-
Annals of Family Medicine . Sep/Oct2019, Vol. 17 Issue 5, p412-418. 7p. - Publication Year :
- 2019
-
Abstract
- <bold>Purpose: </bold>Family physicians need simple yet comprehensive algorithms to discriminate between community-dwelling older persons who are at increased risk of dementia and those who are not. We aimed to investigate associations between incident dementia and responses to a single question regarding subjective memory complaints (SMC) combined with scores on 2 simple memory tests that are easy to use in the primary care setting.<bold>Methods: </bold>Analyses were based on data from 3,454 community-dwelling older persons who participated in the 6- to 8-year Prevention of Dementia by Intensive Vascular Care (preDIVA) trial, yielding 21,341 person-years of observation. Participants were considered a single cohort. We used Cox models to assess separate and combined associations of SMC, an imperfect score on the Mini-Mental State Examination delayed recall item (MMSE-5), and an imperfect score on the Visual Association Test (VAT) with future dementia.<bold>Results: </bold>Subjective memory complaints alone were associated with future dementia (hazard ratio [HR] = 3.01; 95% CI, 2.31-3.94; P <.001), as were the MMSE-5 (HR = 2.14; 95% CI, 1.59-2.87; P <.001) and VAT (HR = 3.19; 95% CI, 2.46-4.13; P <.001) scores. After a median follow-up of 6.7 years, the occurrence of dementia ranged from 4% to 30% among persons with SMC, depending on the MMSE-5 and VAT scores. These test scores did not substantially alter the association with future dementia for persons without SMC.<bold>Conclusions: </bold>In persons with SMC, the strength of the association between future dementia and an imperfect MMSE-5 score depends substantially on the VAT score. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15441709
- Volume :
- 17
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Annals of Family Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 138633377
- Full Text :
- https://doi.org/10.1370/afm.2443