Back to Search
Start Over
Pregnancy does not adversely impact diagnostic tests for HTLV-1/2 infection.
- Source :
-
PLoS Neglected Tropical Diseases . 9/12/2019, Vol. 13 Issue 9, p1-7. 7p. - Publication Year :
- 2019
-
Abstract
- Mother-to-child-transmission (MTCT) of human T-cell lymphotropic virus type-1(HTLV-1) contributes disproportionately to the burden of HTLV-1 associated diseases. All preventive measures to avoid MTCT rely on the identification of infected mothers. However, the impact of pregnancy on HTLV-1 diagnosis has not been clearly assessed. Paired samples from 21 HTLV-1 infected women taken during pregnancy and while not pregnant were analysed by CMIA and PCR. The signal-to-cut-off values (S/CO) were higher during pregnancy than in the paired non-pregnant samples. HTLV-1 proviral load did not alter significantly by pregnant state. S/CO positively correlated with HTLV proviral load. Pregnancy does not impair the diagnosis of HTLV-1/2, by either immunological (CMIA) or molecular (qPCR/nPCR) tests. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HTLV
*IMPACT testing
*DIAGNOSIS methods
*PREGNANCY
Subjects
Details
- Language :
- English
- ISSN :
- 19352727
- Volume :
- 13
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- PLoS Neglected Tropical Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 138582286
- Full Text :
- https://doi.org/10.1371/journal.pntd.0007736