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The construction of an effective far-red fluorescent and colorimetric platform containing a merocyanine core for the specific and visual detection of thiophenol in both aqueous medium and living cells.
- Source :
-
New Journal of Chemistry . 9/21/2019, Vol. 43 Issue 35, p14139-14144. 6p. - Publication Year :
- 2019
-
Abstract
- Thiophenol (PhSH) is toxic to the environment and biological systems although it is an indispensable material in the synthetic processes of chemical products. In this work, we designed and synthesized a malonitrile-based colorimetric and deep-red emission fluorescent dosimeter specifically for thiophenol detection by switching on the intramolecular charge transfer process. The 2,4-dinitrobenzene moiety in the probe could be cleaved by thiophenol, which led to strong deep-red fluorescence increase at 645 nm (50-fold) with a low detection limit of 9 nM. The maximum plateau of emission intensity was reached in about 30 min after the addition of thiophenol. Simultaneously, the presence of thiophenol could result in a prominent color change from orange to blue. Furthermore, the dosimeter could quantitatively sense thiophenol spiked in water samples and successfully visualize thiophenol in living SH-SY5Y cells. [ABSTRACT FROM AUTHOR]
- Subjects :
- *INTRAMOLECULAR charge transfer
*CHEMICAL processes
*MELANOPSIN
*BIOLOGICAL systems
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 43
- Issue :
- 35
- Database :
- Academic Search Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 138522204
- Full Text :
- https://doi.org/10.1039/c9nj03020d