儿童意外吸人磷化铝中毒55例临床分析及文献.

Objective: To analyze the clinical characteristics, treatment methods and cause of death of aluminium phosphide poisoning in children. Methods: The clinical data of 55 cases of children with accidental inhalation of aluminum phosphide poisoning in our hospital from 2014 to 2018 (31 cases of mild poisoning and 14 cases of severe poisoning ) were analyzed, including the age, gender, onset seasons, poisoning inhalation time, visit time and examination results. Results: In the 55 cases, 10 cases died. The average inhalation time of mild poisoning was 25.1 hours, of which the severe poisoning was 185.4 hours, and the average visit time were 14.6 hours and 38.5 hours separately. The clinical manifestations were nausea and vomiting in 55 cases (100%), dizziness and pale in 14 cases (25%), palpitation in 16 cases (29%), respiratory failure in 14 cases (25%), severe arrhythmia in 8 cases (14.5%), hypotension and cardiogenic shock in 10 cases (18%). Electrocardiogram examination were analyzed: 1 case of supraventricular tachycardia, 4 cases of ventricular tachycardia, 1 case of grade 2 II atrioventricular block, 5 cases of sinus arrhythmia, and 26 cases of sinus tachycardia. Laboratory results followed: myocardial enzymes were elevated in 19 cases (34.5%), liver function were abnormal in 12 cases (21.8%), 6 cases (10.9%) had abnormal renal function and 14 cases (25%) had metabolic acidosis. Treatment is mainly symptomatic support treatment. All of them were severe poisoned and died from circulatory failure. Conclusion: The mortality of aluminium phosphide poisoning is very high and the cause of death is circulatory failure. There are no special detoxification drugs now, so it is important to diagnose early and treatment comprehensively. [ABSTRACT FROM AUTHOR]