Iodine-catalyzed direct allylation of chiral oxazolidinones by the amide-aldehyde-alkene condensation.

• Direct allylation of chiral oxazolidinone with aldehydes and olefins. • I 2 -catalyzed amide-aldehyde-olefin condensation. • From inexpensive and abundant un-activated olefins. An iodine-catalyzed direct allylation of chiral oxazolidinones with aldehydes and alkenes has been developed. The reaction proceeds, without use of any bases or metals, directly converted the 3-chiral oxazolidinones into N -allylated oxazolidinones. Additionally, the 3-chiral allylamine skeleton was constructed and the diastereomers were isolated by simple column chromatography. [ABSTRACT FROM AUTHOR]