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Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae.

Authors :
Parisi, Cristina
Failla, Mariacristina
Fraix, Aurore
Rolando, Barbara
Gianquinto, Eleonora
Spyrakis, Francesca
Gazzano, Elena
Riganti, Chiara
Lazzarato, Loretta
Fruttero, Roberta
Gasco, Alberto
Sortino, Salvatore
Source :
Chemistry - A European Journal. 8/22/2019, Vol. 25 Issue 47, p11080-11084. 5p.
Publication Year :
2019

Abstract

Two novel NO photodonors (NOPDs) based on BODIPY and Rhodamine antennae activatable with the highly biocompatible green light are reported. Both NOPDs exhibit considerable fluorescence emission and release NO with remarkable quantum efficiencies. The combination of the photoreleasing and emissive performance for both compounds is superior to those exhibited by other NOPDs based on similar light‐harvesting centres, making them very intriguing for image‐guided phototherapeutic applications. Preliminary biological data prove their easy visualization in cell environment due to the intense green and orange‐red fluorescence and their photodynamic action on cancer cells due to the NO photo‐liberated. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09476539
Volume :
25
Issue :
47
Database :
Academic Search Index
Journal :
Chemistry - A European Journal
Publication Type :
Academic Journal
Accession number :
138204348
Full Text :
https://doi.org/10.1002/chem.201902062