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A modified partial likelihood score method for Cox regression with covariate error under the internal validation design.

Authors :
Zucker, David M.
Zhou, Xin
Liao, Xiaomei
Li, Yi
Spiegelman, Donna
Source :
Biometrics. Jun2019, Vol. 75 Issue 2, p414-427. 14p.
Publication Year :
2019

Abstract

We develop a new method for covariate error correction in the Cox survival regression model, given a modest sample of internal validation data. Unlike most previous methods for this setting, our method can handle covariate error of arbitrary form. Asymptotic properties of the estimator are derived. In a simulation study, the method was found to perform very well in terms of bias reduction and confidence interval coverage. The method is applied to data from the Health Professionals Follow‐Up Study (HPFS) on the effect of diet on incidence of Type II diabetes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006341X
Volume :
75
Issue :
2
Database :
Academic Search Index
Journal :
Biometrics
Publication Type :
Academic Journal
Accession number :
138203528
Full Text :
https://doi.org/10.1111/biom.13012