CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response.

The article discusses a study on the skin inflammation increase in atomic dermatitis (AM) by way of the inhibitory receptor (IR) CD300a. Results suggested a down-regulatory role for CD300a in AD inflammation as in previous demonstrations on other allergic and nonallergic diseases, and their murine models. Also noted is the possible use of CD300a-specific activation as a support in AD anti-inflammatory strategy.