Back to Search Start Over

SU67POLYGENIC RISK SCORES DERIVED FROM A TOURETTE SYNDROME GWAS PREDICT PRESENCE OF TICS IN THE AVON LONGITUDINAL STUDY OF PARENTS AND CHILDREN (ALSPAC) COHORT.

Authors :
Abdulkadir, Mohamed
Mathews, Carol
Scharf, Jeremiah
Yu, Dongmei
Tischfield, Jay
Heiman, Gary
Hoekstra, PJ
Dietrich, Andrea
Source :
European Neuropsychopharmacology. 2019 Supplement4, Vol. 29, pS1302-S1303. 2p.
Publication Year :
2019

Abstract

Highlights from the article: Su67polygenic risk scores derived from a tourette syndrome gwas predict presence of tics in the avon longitudinal study of parents and children (alspac) cohort The authors investigated the role of polygenic risk scores (PRS) derived from a TS genome-wide association study (GWAS) in relation to the occurrence of tics and associated traits in a general population cohort. B Discussion: b The authors found a significant polygenic component of tics occurring in a general population cohort based on PRS derived from a GWAS of individuals with a TS diagnosis.

Details

Language :
English
ISSN :
0924977X
Volume :
29
Database :
Academic Search Index
Journal :
European Neuropsychopharmacology
Publication Type :
Academic Journal
Accession number :
137723960
Full Text :
https://doi.org/10.1016/j.euroneuro.2018.08.431