Back to Search
Start Over
Effects of a topical lotion containing aminophylline, caffeine, yohimbe, l‐carnitine, and gotu kola on thigh circumference, skinfold thickness, and fat mass in sedentary females.
- Source :
-
Journal of Cosmetic Dermatology . Aug2019, Vol. 18 Issue 4, p1037-1043. 7p. - Publication Year :
- 2019
-
Abstract
- Background and objective: Topical aminophylline, caffeine, yohimbe, l‐carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was enhanced via the topical application of this lotion. Methods: This was a double‐blind, placebo‐controlled, within‐group study that investigated the effects of Lipoxyderm™ on thigh fat mass, circumference, and skinfold thickness. Seven participants underwent pre/post‐exercise testing for weight, bilateral thigh circumference/skinfold thickness, and body composition/thigh fat mass assessment via dual‐energy X‐ray absorptiometry. Participants followed a hypocaloric diet, walked 150 minutes/wk, and were randomly assigned to apply a placebo to one leg and Lipoxyderm™ to their other leg for 28 days. Separate two‐way mixed factorial repeated measures ANOVAs were used to compare the effects of Lipoxyderm™ to the placebo on thigh circumference, skinfold thickness, and fat mass. Results: A significant time x group interaction was found for thigh circumference (F1,6 = 18.2, P = 0.005), skinfold thickness (F1,6 = 14.6, P = 0.009), and fat mass (F1,6 = 37.1, P = 0.001). Conclusions: A twice‐daily topical application of Lipoxyderm™ for 28 days compared to a placebo combined with a walking program and a restricted caloric intake is more effective at reducing thigh circumference (1.2 vs 0.8 cm), thigh skinfold thickness (3.7 vs 2.0 mm), and thigh fat mass (100.0 g vs 57.3 g). [ABSTRACT FROM AUTHOR]
- Subjects :
- *CENTELLA asiatica
*SKINFOLD thickness
*THIGH
*DUAL-energy X-ray absorptiometry
*FAT
Subjects
Details
- Language :
- English
- ISSN :
- 14732130
- Volume :
- 18
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Cosmetic Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 137621585
- Full Text :
- https://doi.org/10.1111/jocd.12801