后路内固定融合术对胸腰段脊柱骨折患者椎体参数与创伤应激状态的影响研究

Objective: To investigate the influence of posterior internal fixation and fusion on the vertebral body parameters and trauma stress state of patients with thoracolumbar spine fracture. Methods: 60 patients with thoracolumbar spine fracture during the time of November 2016 to November 2017 were selected for the study, and they were divided into control group(anterior internal fixation and fusion group) 30 cases and observation group(posterior internal fixation and fusion group) 30 cases. Then the variation of vertebral body parameters and serum ACTH, Cor and TNF-α of two groups before and after the operation were compared. Results: At one month and six months after surgery, the vertebral body parameters of the two groups were better than those before surgery, which were better in the observation group than those of the control group(P<0.05). At one week after surgery, the level of serum ACTH, Cor of both groups were higher, which were lower in the observation group than those in the control group(P<0.05), the TNF-α level of observation group was lower in observation group than that of the control group(P<0.05). At two weeks after surgery, the serum ACTH level of observation group was much lower than those of the control group, which were even lower than those before surgery. The serum Cor and TNF-αlevels of observation group were also lower than those of the control group(P<0.05). Conclusions: The influence of posterior internal fixation and fusion for the vertebral body parameters and trauma stress state of patients with thoracolumbar spine fracture are relatively better. [ABSTRACT FROM AUTHOR]