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Pd-Catalyzed Remote Meta-C-H Functionalization of Phenylacetic Acids Using a Pyridine Template.

Authors :
Zhong Jin
Ling Chu
Yan-Qiao Chen
Jin-Quan Yu
Source :
Organic Letters. 1/19/2018, Vol. 20 Issue 2, p425-428. 4p.
Publication Year :
2018

Abstract

An effective pyridine based U-shaped template has been developed to enable a diverse range of meta-C-H functionalizations of phenylacetic acid scaffolds. This new template has extended the reaction scope to cross-coupling with ArBF3K as well as iodination using 1,3-diiodo-5,5-dimethylhydantoin as the iodination reagent. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15237060
Volume :
20
Issue :
2
Database :
Academic Search Index
Journal :
Organic Letters
Publication Type :
Academic Journal
Accession number :
137315133
Full Text :
https://doi.org/10.1021/acs.orglett.7b03336