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Courses for horses: Rethinking the use of proton pump inhibitors in the treatment of equine gastric ulcer syndrome.
- Source :
-
Equine Veterinary Education . Aug2019, Vol. 31 Issue 8, p441-446. 6p. - Publication Year :
- 2019
-
Abstract
- Summary: Oral omeprazole has been the cornerstone of equine gastric ulcer syndrome (EGUS) treatment for nearly 20 years. However, approximately 15–30% of equine squamous gastric disease (ESGD) cases and 75% of equine glandular gastric disease (EGGD) cases fail to heal within current treatment guidelines. Recently, a number of factors that may affect the efficacy of oral omeprazole have been highlighted and the pharmacodynamics of a number of novel proton pump inhibitors (PPIs) have been described in the horse. The purpose of this article is to review the factors that affect oral omeprazole efficacy, with the goal of maximising therapeutic response, and the novel PPIs recently described. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROTON pump inhibitors
*THERAPEUTICS
*GASTRIC diseases
*HORSES
*ULCERS
*OMEPRAZOLE
Subjects
Details
- Language :
- English
- ISSN :
- 09577734
- Volume :
- 31
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Equine Veterinary Education
- Publication Type :
- Academic Journal
- Accession number :
- 137267621
- Full Text :
- https://doi.org/10.1111/eve.12894