Lipid accumulation in Cyprinus carpio (Linnaeus, 1785) liver induced by thiamethoxam.

The aim of the present study is to investigate the effects of a thiamethoxam based insecticide on the expression of lipid droplets in Common Carp, Cyprinus Carpio (Linnaeus, 1785) liver. The selected concentrations of the test pesticide were 6.6 mg/L, 10 mg/L and 20 mg/L under laboratory conditions for an acute period of 96 h. The Sudan III staining method was applied for detection of fatty degeneration in the fish hepatocytes. Overall, we found that the fat storage in the liver cells increased proportionally with the increased pesticide concentrations. The results demonstrated fat accumulation in the fish liver which in addition, could be used as an easy to perform and relatively inexpensive biological tool for studying the effects of pesticide contamination on fish. [ABSTRACT FROM AUTHOR]