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Multigram Synthesis of Functionalized Spirocyclic Diazirines.

Authors :
Martyloga, Oleksandr V.
Myronenko, Artamon
Tkachenko, Anton M.
Matvienko, Vitalii O.
Kuchkovska, Yuliya O.
Grygorenko, Oleksandr O.
Source :
European Journal of Organic Chemistry. 6/23/2019, Vol. 2019 Issue 23, p3744-3750. 7p.
Publication Year :
2019

Abstract

An approach to the synthesis of spirocyclic diazirines from cyclic ketones was examined on a series of carbo‐ and heterocyclic substrates containing the amine or carboxylic acid moiety. A mini‐library of stereochemically diverse functionalized spirocyclic diazirines was synthesized on a multigram scale with 30–81 % yield. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1434193X
Volume :
2019
Issue :
23
Database :
Academic Search Index
Journal :
European Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
137109538
Full Text :
https://doi.org/10.1002/ejoc.201900485