Optical coherence tomography for dynamic axial correction of an optical end-effector for robot-guided surgical laser ablation.

Robot-guided laser ablation for surgical applications potentially offers many advantages compared to by-hand mechanical tissue cutting. However, given that tissue can be rough and/or uneven, ablation quality can be compromised if the beam waist deviates significantly from the target tissue surface. Therefore, we present a method that uses optical coherence tomography (OCT) for dynamic refocusing of robot-guided surgical laser ablation. A 7-DOF robotic manipulator with an OCT-equipped optical payload was used to simulate robotic guided laser osteotomy. M-mode OCT feedback is used for continuous surface detection to correct for axial deviations along the ablation path due to surface nonuniformity. We were able to show that such a correction scheme could maintain the beam waist within the depth of focus for surface variation as aggressive as 45 deg with feed rates up to 1 mm/s. Strategies for implementation in surgical and nonsurgical applications are examined. [ABSTRACT FROM AUTHOR]