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On Sensitivity Value of Pair-Matched Observational Studies.
- Source :
-
Journal of the American Statistical Association . Jun2019, Vol. 114 Issue 526, p713-722. 10p. - Publication Year :
- 2019
-
Abstract
- This article proposes a new quantity called the "sensitivity value," which is defined as the minimum strength of unmeasured confounders needed to change the qualitative conclusions of a naive analysis assuming no unmeasured confounder. We establish the asymptotic normality of the sensitivity value in pair-matched observational studies. The theoretical results are then used to approximate the power of a sensitivity analysis and select the design of a study. We explore the potential to use sensitivity values to screen multiple hypotheses in the presence of unmeasured confounding using a microarray dataset. Supplementary materials for this article are available online. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SCIENTIFIC observation
*ASYMPTOTIC normality
*SENSITIVITY analysis
Subjects
Details
- Language :
- English
- ISSN :
- 01621459
- Volume :
- 114
- Issue :
- 526
- Database :
- Academic Search Index
- Journal :
- Journal of the American Statistical Association
- Publication Type :
- Academic Journal
- Accession number :
- 136978873
- Full Text :
- https://doi.org/10.1080/01621459.2018.1429277