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Fabrication of a novel antibacterial TPU nanofiber membrane containing Cu-loaded zeolite and its antibacterial activity toward Escherichia coli.
- Source :
-
Journal of Materials Science . Sep2019, Vol. 54 Issue 17, p11682-11693. 12p. 5 Diagrams, 2 Charts, 4 Graphs. - Publication Year :
- 2019
-
Abstract
- A novel antibacterial thermoplastic polyurethane (TPU) nanofiber membrane was fabricated by electrospinning with the aid of Cu-loaded NaX zeolite (CuX), which showed excellent and long-lasting antibacterial activity against Escherichia coli (E. coli). The crystalline structure, morphology and composition of the obtained NaX zeolite, CuX and CuX/TPU nanofiber membrane were analyzed by X-ray diffraction (XRD), scanning electron microscope (SEM) and X-ray fluorescence (XRF), respectively. The antibacterial activity of CuX/TPU nanofiber membrane against E. coli was investigated by inhibition zone method and plate-counting method, and it is indicated that the inactivation efficiency was increased from 58.40 to 99.85% with increasing the addition of CuX from 5 to 30% in 4 h. The result of kinetics study indicated that the disinfection process accorded with the pseudo-first-order model. The possible antibacterial mechanism was also proposed that the released Cu2+ by CuX in nanofiber membrane destroyed the cell wall and penetrated plasma membrane of E. coli. It is expected that this CuX/TPU nanofiber membrane with excellent antibacterial activity would be a promising candidate for biomedical applications. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00222461
- Volume :
- 54
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of Materials Science
- Publication Type :
- Academic Journal
- Accession number :
- 136939313
- Full Text :
- https://doi.org/10.1007/s10853-019-03727-x