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Gain control of NMDA-receptor currents by intracellular sodium.
- Source :
-
Nature . 12/3/1998, Vol. 396 Issue 6710, p469. 6p. 2 Diagrams, 40 Graphs. - Publication Year :
- 1998
-
Abstract
- Presents research which showed that [Na+]i regulates the function of N-methyl-D-aspartate (NMDA) receptors. Role of Na+ in the nervous system; Effects of increases in intracellular Na+ concentration; Increases in NMDA-receptor-mediated whole-cell currents and NMDA-receptor single-channel activity; Sensitivity of channels to Na+; Raising [Na+]i selectivity; Change in postsynaptic [Na+]i during neuronal activity.
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 396
- Issue :
- 6710
- Database :
- Academic Search Index
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 1366895
- Full Text :
- https://doi.org/10.1038/24877