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Profile of endometriosis in the aging female rhesus monkey.
- Source :
-
Journals of Gerontology Series A: Biological Sciences & Medical Sciences . Jan98, Vol. 53A Issue 1, pM3-M7. 5p. - Publication Year :
- 1998
-
Abstract
- <bold>Background: </bold>A retrospective analysis was conducted on necropsy records from a large rhesus monkey colony to evaluate the age-related prevalence of endometriosis.<bold>Methods: </bold>A total of 314 records collected over a 15-year period were analyzed, yielding 66 monkeys with histologically verified endometriosis and 248 control subjects.<bold>Results: </bold>The analyses demonstrated that the incidence of endometriosis increases progressively across the life span, ultimately impacting 21-45% of aged monkeys over 20 years of age.<bold>Conclusions: </bold>Because mild disease is often not diagnosed premortem, the endocrine and immune sequelae of endometriosis may be a potential confound in even nonreproductive research with aging primates. Prior research-related events influence the occurrence and severity of endometriosis in these long-lived animals, and specifically could have contributed to the high prevalence of endometriosis in this particular monkey colony. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10795006
- Volume :
- 53A
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 136553785
- Full Text :
- https://doi.org/10.1093/gerona/53a.1.m3