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A hypercoagulable state leading to venous limb gangrene associated with occult lung adenocarcinoma.

Authors :
Waite, Matthew M. A.
Martinelli, Anthony W.
Preston, Stephen D.
Gudgin, Emma
Symington, Emily
Rintoul, Robert C.
Peryt, Adam
Coughlin, Patrick
Hayes, Paul
Gilligan, David
Besser, Martin
Source :
Clinical Case Reports. May2019, Vol. 7 Issue 5, p888-892. 5p.
Publication Year :
2019

Abstract

Key Clinical Message: We report a case of lung adenocarcinoma‐associated hypercoagulability leading to venous limb gangrene, managed successfully with argatroban and then dabigatran. Use of idarucizumab permitted diagnostic investigations, leading to targeted antineoplastic therapy with crizotinib, surgical resection with curative intent, and continued survival over 2 years after the index event. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*GANGRENE
*LUNGS
*ADENOCARCINOMA

Details

Language :
English
ISSN :
20500904
Volume :
7
Issue :
5
Database :
Academic Search Index
Journal :
Clinical Case Reports
Publication Type :
Academic Journal
Accession number :
136381335
Full Text :
https://doi.org/10.1002/ccr3.2106