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Platycosides P and Q, two new triterpene saponins from Platycodon grandiflorum.
- Source :
-
Journal of Asian Natural Products Research . May2019, Vol. 21 Issue 5, p419-425. 7p. - Publication Year :
- 2019
-
Abstract
- The EtOH extract of the roots of Platycodon grandiflorum afforded two new triterpene saponins platycoside P (1) and platycoside Q (2). Their structures were elucidated based on spectroscopic means and hydrolysis products. These compounds were evaluated for inhibitory activity against LPS-induced TNF-α production in RAW 246.7 macrophages. Compounds 1 and 2 showed inhibitory activity with the inhibition ratios (%) of 38.6 and 44.1 at 50 μM, respectively. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 21
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 136090477
- Full Text :
- https://doi.org/10.1080/10286020.2018.1488835