Rehmanniae Radix Preparata suppresses bone loss and increases bone strength through interfering with canonical Wnt/β-catenin signaling pathway in OVX rats.

The article offers a study that reveals the effect of anti-osteoporotic of Rehmanniae Radix Preparata (RRP) in ovariectomized (OVX) rats. Topics discussed include RRP helps to improve bone quality in OVX rats through the regulation of bone homeostasis and suggests for the development of anti-osteoporotic drugs, mentions the treatment of OVX rats with RRP aqueous extract that helps to rebuilt bone homeostasis, and information on the improving trabecular distribution in the femurs of OVX rats.