تأثیر فعالیت مقاومتی فزاینده و مصرف شیر سویا بر میزان سرمی هورمون فاکتور تفکیک رشد- 8 زنان سالمند

Introduction: Aging is concomitant with muscle atrophy and common alterations in hypertrophic hormones. Besides, resistance training and protein consumption modify these changes. Hence, the current study aimed to assess the effects of progressive resistance exercise and soy milk on serum levels of growth differentiation factor 8 in older adult women. Material & Methods: This quasi-experimental study recruited Twenty-four aged women randomly assigned into control (n=8), progressive resistance exercise + soy milk (n=8), and soy milk (n=8) groups. The experimental groups took part in exercise-diet intervention for 12 weeks (3 d/w). Anthropometric features, ability, and serum levels of growth differentiation factor 8 were collected before and after the interventions. All data were calculated by two-way ANOVA and Bonferroni post-hoc at p<0.05 with Stata 12. Results: Growth differentiation factor 8 levels significantly diminished in both progressive resistance exercise + soy milk and soy milk groups compared with control and pre-intervention (p<0.05). Furthermore, ability of the progressive resistance exercise + soy milk group showed significant improvements compared with control and pre-intervention (p<0.05). There was no alteration in anthropometric features of any of the groups (p>0.05). Conclusion: Twelve-week exercise-diet intervention resulted in decrease of growth differentiation factor 8 in older adult women, which could reverse age-related skeletal muscle atrophy. Furthermore, the ability of older women developed via exercise-diet interventions, which proves the positive functional-physiological effects of exercise and protein in older adult women skeletal muscle. Consequently, social activities and life quality could promote. [ABSTRACT FROM AUTHOR]