Abstract 15332: Impact of Post-Stenting Balloon Dilatation on 5-Year Clinical Outcomes in Patients With Acute Coronary Syndrome Underwent Percutaneous Coronary Intervention.

Background: Post-stenting balloon dilation is associated with improvement of stent deploymanet and better angiographic results in percutaneous coronary intervention (PCI). However, it had not been evaluated competently in setting of acute coronary syndrom (ACS) undergoing PCI. There are limited data regarding the impact of post-stenting balloon dilatation on long term clinical outcomes in ACS patients. Methods: Procedural details of total 2533 ACS patients (693 ST elevation myocardial infarction, STEMI patients, 640 Non-ST elevation MI, NSTEMI patients, and 1220 Unstable Angina patients) underwent PCI were examined. Patients were divided into two groups; 1) NO Post dilatation group (N=1047) and 2) Post dilatation group (N=1506). Individual and composite major clinical otucomes including major adverse cardiac events (MACE), the composite of total death, MI,stroke and revascularization, were compared between the two groups up to 5 years. Results: At 5 years follow up, post dilatation group had signficantly lower target vessel revascularization (TVR, HR: 0.716, 95% CI: 0.524 to 0.978 ;p = 0.035), non-TVR (HR: 0.538, 95% CI: 0.319 to 0.908; p = 0.020), stroke (HR: 0.778, 95% CI: 0.638 to 0.948; p = 0.013) and MACE (HR: 0.749, 95% CI : 0.592 to 0.947; p = 0.016) than No post dilatation group (Table). Using multivariate logestic regression, and after adjusting for potential risk factors, post diltation patients had lower total MACE (HR: 0.711, 95% CI : 0.524 to 0.965; p = 0.029), including TVR and stroke. Conclusion: In ACS patients undergoing PCI, post dilatation was associated with lower risk of TVR, CVA and total MACE up to 5 years clinical follow up. [ABSTRACT FROM AUTHOR]