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Development of hand function during the first year of life in children with unilateral cerebral palsy.
- Source :
-
Developmental Medicine & Child Neurology . May2019, Vol. 61 Issue 5, p563-569. 7p. - Publication Year :
- 2019
-
Abstract
- <bold>Aim: </bold>To identify developmental trajectories of hand function in infants aged 3 months to 12 months with unilateral cerebral palsy (CP).<bold>Method: </bold>Infants at high risk of unilateral CP were recruited from 3 months of age from follow-up programmes and clinics in Sweden, the Netherlands, Italy, and Australia. Measurements on the Hand Assessment for Infants (HAI) were completed until 12 months of age. Group-based trajectory modelling was used to identify subgroups of infants with similar trajectories of development. Multinomial logistic regression determined associations between demographic variables and trajectory membership.<bold>Results: </bold>Ninety-seven infants (52 males, 45 females; median gestational age 38wks [interquartile range 30-40wks]) were included. Infants were assessed between two and seven times (mean 4, SD 1.2) with a total of 387 observations. A three-group trajectory model identified a 'low-functioning group' (n=45: 46%), 'moderate-functioning group' (n=30: 31%), and 'high-functioning group' (n=22: 23%). Mean posterior probabilities (0.91-0.96) and odds of correct classification (26.3-33.2) indicated good model fit. Type of brain lesion, sex, side of hemiplegia, country, gestational age, and access to intensive intervention were not associated with group membership.<bold>Interpretation: </bold>Three trajectories of hand function development for infants with unilateral CP were identified and indicate some greater distinctions between groups with increasing age. The HAI is a valuable measure, capturing development of hand function of infants with unilateral CP over time.<bold>What This Paper Adds: </bold>Three distinct developmental trajectories of hand function in infants with unilateral cerebral palsy were identified. A low-functioning group made little progress in development of hand function in the first year of life. The degree of impairment on the impaired hand at 6 months of age is highly associated with trajectory membership. Infants with all types of brain lesion were represented across each trajectory group. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00121622
- Volume :
- 61
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Developmental Medicine & Child Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 135746728
- Full Text :
- https://doi.org/10.1111/dmcn.14091