The renin-angiotensin-aldosterone system in atrial fibrillation: a new therapeutic target?

Investigates the role of renin-angiotensin-aldosterone system (RAAS) in atrial fibrillation and its potential as a therapeutic target. Overview of atrial fibrillation; Usefulness of the blockade of the RAAS in several cardiovascular disorders; Beneficial effect of losartan in the Losartan Intervention for Endpoint reduction in hypertension trial; Left ventricular hypertrophy; Role of RAAS on thrombogenesis.