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Four-component, three-step cascade reaction: an effective synthesis of indazole-fused triazolo[5,1-c]quinoxalines.
Four-component, three-step cascade reaction: an effective synthesis of indazole-fused triazolo[5,1-c]quinoxalines.
- Source :
-
New Journal of Chemistry . 3/21/2019, Vol. 43 Issue 11, p4333-4337. 5p. - Publication Year :
- 2019
-
Abstract
- An efficient four-component, three-step cascade reaction was developed for the synthesis of indazole-fused triazolo[5,1-c]quinoxalines from o-azido aldehyde, o-iodoaniline, phenylacetylene, and sodium azide. The methodology involves the sequential formation of 2H-indazole, then azide–alkyne cycloaddition, followed by C–N coupling, and finally intramolecular cross-dehydrogenative C–C coupling. Notable features of this protocol include simple starting materials, reduced synthetic steps, and good yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SODIUM azide
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 43
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 135233118
- Full Text :
- https://doi.org/10.1039/c8nj06299d