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HColonDB: A Database for Human Colon Cancer Research.

Authors :
Mao, Xiaodan
Xu, Yichen
Jiang, Zhenran
Source :
Journal of Computational Biology. Mar2019, Vol. 26 Issue 3, p218-224. 7p.
Publication Year :
2019

Abstract

HColonDB (Human Colon cancer Database) is an important database which integrates genes, pathways, networks, drugs, and other information related to colon cancer. The purpose of the database is to provide a platform for the systematic research of colon cancer. The relationships between genes and pathways, genes and networks, and networks and pathways are obtained from the database KEGG. Furthermore, the information of the drugs used to treat colon cancer is available in HColonDB, which is collected and organized from DrugBank and PubChem database. In brief, we have summarized 81 genes, 112 pathways, 108 networks, and 15 drugs associated with colon cancer. The current version of HColonDB contains 322 associations between genes and pathways, 242 associations between genes and networks, and 68 associations between networks and pathways. In addition, HColonDB provides a friendly interface for users to browse and search. We hope that the database can make it more convenient for researchers to get the data they need and help in the treatment of colon cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10665277
Volume :
26
Issue :
3
Database :
Academic Search Index
Journal :
Journal of Computational Biology
Publication Type :
Academic Journal
Accession number :
135108636
Full Text :
https://doi.org/10.1089/cmb.2018.0193