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α -Tetralonyl Glucosides from the Green Walnut Husks of Juglans mandshurica and Their Antiproliferative Effects.
α -Tetralonyl Glucosides from the Green Walnut Husks of Juglans mandshurica and Their Antiproliferative Effects.
- Source :
-
Planta Medica . 2019, Vol. 85 Issue 4, p335-339. 5p. - Publication Year :
- 2019
-
Abstract
- Two new α -tetralonyl glucosides, (4 S)-4,5,8-trihydroxy- α -tetralone-5- O - β -D-glucopyranosyl(1 → 6)- β -D-glucopyranoside (1) and (4 S)-4,8-dihydroxy- α -tetralone-4- O - β -D-glucopyranosyl(1 → 6)- β -D-glucopyranoside (2), together with eight known compounds (3 – 10) were isolated from the green walnut husks of Juglans mandshurica. The structural characterization of all compounds was performed by spectroscopic analyses, including 1D and 2D NMR and HR-ESI-MS experiments. The isolated compounds were assayed for their cytotoxicity against two human cancer cell lines, A549 and HeLa. Four compounds (7 – 10) exhibited inhibitory effects against two human cancer cell lines with GI50 values between 1.3 and 5.8 µM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00320943
- Volume :
- 85
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Planta Medica
- Publication Type :
- Periodical
- Accession number :
- 134933323
- Full Text :
- https://doi.org/10.1055/a-0832-2328