Coccidiosis in dogs—100 years of progress.

Highlights • This paper reviews biology of Cystoisospora infections in dogs, including taxonomy, diagnosis, epidemiology, and treatment. • Endogenous stages of C. canis, C. ohioensis, and C. ohioensis -like coccidia are compared. • Drugs containing toltrazuril were found most efficacious for treating canine coccidiosis. Abstract Until 1970, coccidian parasites of dogs were considered to have a direct fecal-oral life cycle like Eimeria in poultry. They were thought to be non-host specific and infect both dogs and cats. Studies conducted in the 1970s revealed that dog coccidia were host-specific and had transport or paratenic hosts that were infected with an encysted stage containing a single organism, the monozoic tissue cyst. There are still considerable confusion and uncertainties concerning the life cycles and pathogenicity of coccidian parasites of dogs. The present paper reviews the history, taxonomy, life cycles, pathogenicity, epidemiology, diagnosis, and treatment of conventional coccidian parasites previously called Isospora spp., currently designated Cystoisospora spp. that infect canines. [ABSTRACT FROM AUTHOR]