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Diastereoselective Synthesis of Cyclic sp3-Enriched cis-ß-Alkoxysulfonyl Chlorides.

Authors :
Sokolov, Andriy
Golovach, Sergey
Kozlinsky, Ihor
Dolia, Krystyna
Tolmachev, Andrey A.
Kuchkovska, Yuliya
Grygorenko, Oleksandr O.
Source :
Synthesis. 2019, Vol. 51 Issue 4, p948-958. 11p.
Publication Year :
2019

Abstract

A three-step synthesis of ß-alkoxy-substituted alicyclic sulfonyl chlorides from cyclic alkenes and alcohols is reported. The scope of the method was studied for a range of the substrates with various steric and electronic properties. The title compounds were obtained on a hundred-gram scale in up to 52% overall yield scale as single cis-diastereomers. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397881
Volume :
51
Issue :
4
Database :
Academic Search Index
Journal :
Synthesis
Publication Type :
Academic Journal
Accession number :
134440714
Full Text :
https://doi.org/10.1055/s-0037-1611277