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Low-intensity resistance training with partial blood flow restriction and high-intensity resistance training induce similar changes in skeletal muscle transcriptome in elderly humans.

Low-intensity resistance training with partial blood flow restriction and high-intensity resistance training induce similar changes in skeletal muscle transcriptome in elderly humans.

Authors :
Vechin, Felipe C.
Libardi, Cleiton A.
Conceição, Miguel S.
Damas, Felipe
Cavaglieri, Claudia R.
Chacon-Mikahil, Mara Patricia T.
Coutinho, Luiz L.
Andrade, Sonia C.S.
Neves Jr, Manoel T.
Roschel, Hamilton
Tricoli, Valmor
Baptista, Igor L.
Moriscot, Anselmo A.
Ugrinowitsch, Carlos
Source :
Applied Physiology, Nutrition & Metabolism. 2019, Vol. 44 Issue 2, p216-220. 5p.
Publication Year :
2019

Abstract

We aimed to investigate the mechanisms underlying muscle growth after 12 weeks of resistance training performed with blood flow restriction (RT–BFR) and high-intensity resistance training (HRT) in older individuals. Participants were allocated into the following groups: HRT, RT–BFR, or a control group. High-throughput transcriptome sequencing was performed by the Illumina HiSeq 2500 platform. HRT and RT–BFR presented similar increases in the quadriceps femoris cross-sectional area, and few genes were differently expressed between interventions. The small differences in gene expression between interventions suggest that similar mechanisms may underpin training-induced muscle growth. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17155312
Volume :
44
Issue :
2
Database :
Academic Search Index
Journal :
Applied Physiology, Nutrition & Metabolism
Publication Type :
Academic Journal
Accession number :
134326961
Full Text :
https://doi.org/10.1139/apnm-2018-0146