Back to Search
Start Over
Benefits of laparoscopic surgery compared to open standard surgery for gastric carcinoma in elderly patients: propensity score-matching analysis.
- Source :
-
Surgical Endoscopy & Other Interventional Techniques . Feb2019, Vol. 33 Issue 2, p510-519. 10p. 1 Diagram, 8 Charts, 2 Graphs. - Publication Year :
- 2019
-
Abstract
- <bold>Background: </bold>Laparoscopic surgery is frequently performed, and laparoscopic gastrectomy (LG) is also widely performed for gastric cancer. Elderly population with gastric cancer has increased in East Asia, including in Japan.<bold>Methods: </bold>We examined 1131 patients with gastric cancer who underwent laparoscopic and open standard surgeries (OG). A total of 921 patients of age < 75 years (non-E group) and 210 patients of age ≥ 75 years (E group) underwent surgery for gastric cancer. The mortality, morbidity, and prognosis of LG and OG were compared by propensity score-matched analysis.<bold>Results: </bold>Mortality and morbidity in the E group were significantly higher than those in the non-E group (p < 0.05). Propensity score-matching revealed that the incidence of postoperative complications of grade ≥ 2 in the OG subgroup was significantly higher than that in the LG subgroup in the E group (p < 0.05). The overall survival rate of the LG subgroup was significantly higher than that of the OG subgroup in both the non-E and E groups (p < 0.05). The depth of tumor invasion, lymph node metastasis, and the number of dissected lymph nodes were dependent factors for survival in the non-E group, whereas the depth of tumor invasion was the only dependent factor for survival in the E group in the multivariate analysis.<bold>Conclusion: </bold>The survival rate of patients who underwent LG showed significantly good prognosis in both the non-E and E groups, although the E group patients who underwent OG subgroup showed higher severe complication incidences than those who underwent LG subgroup. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LAPAROSCOPIC surgery
*STOMACH cancer treatment
*OLDER patients
*GASTRECTOMY
*MULTIVARIATE analysis
*COMPARATIVE studies
*SURGICAL excision
*LAPAROSCOPY
*LYMPH node surgery
*RESEARCH methodology
*MEDICAL cooperation
*METASTASIS
*PROBABILITY theory
*PROGNOSIS
*RESEARCH
*STOMACH tumors
*SURGICAL complications
*SURVIVAL
*EVALUATION research
*DISEASE incidence
Subjects
Details
- Language :
- English
- ISSN :
- 18666817
- Volume :
- 33
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Surgical Endoscopy & Other Interventional Techniques
- Publication Type :
- Academic Journal
- Accession number :
- 134239484
- Full Text :
- https://doi.org/10.1007/s00464-018-6325-7