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Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy.

Authors :
Lapa, Constantin
Lückerath, Katharina
Kircher, Stefan
Hänscheid, Heribert
Grigoleit, Götz U.
Rosenwald, Andreas
Stolzenburg, Antje
Kropf, Saskia
Einsele, Hermann
Wester, Hans‐Jürgen
Buck, Andreas K.
Kortüm, Klaus M.
Schirbel, Andreas
Source :
British Journal of Haematology. Feb2019, Vol. 184 Issue 3, p440-443. 4p. 2 Diagrams.
Publication Year :
2019

Abstract

Case studies of 32, 62 and 75 years patients are presented with relapsed refractory multiple myeloma, diffuse large B cell lymphoma, and acute lymphoblastic leukaemia. C-X-C-motif chemokine receptor 4 (CXCR4)-directed treatment was offered on a compassionate use basis prior to stem cell transplantation; and initial CXCR4-expression was confirmed in all patients using Pentixafor positron emission tomography/computed tomography and immunohistochemical analysis.

Details

Language :
English
ISSN :
00071048
Volume :
184
Issue :
3
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
134216569
Full Text :
https://doi.org/10.1111/bjh.15096