Fabrication of poly (sudan III) modified carbon paste electrode sensor for dopamine: A voltammetric study.

Abstract Owing to the challenges faced in simultaneous determination of dopamine(DA), uric acid(UA) and ascorbic acid (AA) in mixtures by electrochemical method, the present work is aimed at developing a simple, sensitive and selective sensor using sudan III as the modifier. The poly (sudan III) modified carbon paste electrode (PS/MCPE) was prepared by electropolymerization of sudan III monomer on the surface of bare carbon paste electrode (BCPE). Electrochemical sensing properties of poly (sudan III) MCPE were evaluated by cyclic voltammetry for individual analytes and findings revealed that it has a good electrocatalytic activity towards the determination of dopamine (DA), uric acid (UA) and ascorbic acid (AA) characterized by a low detection limit of 9.3 × 10−6 M, 1 × 10−5 M and 4.5 × 10−5 M for DA, UA and AA, respectively. The scan rate study reveals that the electrode process is adsorption-controlled. The simultaneous determination of the analytes in a mixture showed that the modified electrode exhibits an outstanding selectivity towards DA, UA and AA with their distinct oxidation potentials occurring at 0.14 V, 0.27 V, and −0.07 V, respectively. The fabricated modified electrode sensor exhibited excellent electrocatalytic properties towards the determination of DA, UA and AA with satisfactory results. Graphical abstract Unlabelled Image Highlights • The poly (sudan III)/MCPE was fabricated through electropolymerization method using sudan III as monomer. • The developed sensor exhibited excellent electrocatalytic activity towards the oxidation of DA, UA and AA. • Good LOD and LOQ were obtained. • Real sample analysis was carried out. [ABSTRACT FROM AUTHOR]