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Crystal Structure and Anti-kidney Cancer Activity of Two Novel Coordination Polymers {[Cu2(DCTP)2](H2O)}n and {[Zn5(NTB)4(DMF)2](NH2NMe2)(DMF)3}n
- Source :
-
Russian Journal of Coordination Chemistry . Dec2018, Vol. 44 Issue 12, p824-830. 7p. - Publication Year :
- 2018
-
Abstract
- Abstract: Two new coordination polymers, namely {[Cu2(DCTP)2](H2O)}n (I) (H2DCTP = 4'-(3,5-dicarboxyphenyl)-4,2':6',4''-terpyridine) and {[Zn5(NTB)4(DMF)2](H2NMe2)2(DMF)3}n (II) (H3NTB = 4,4′,4″-nitrilotribenzoic acid, DMF = N,N-dimethylformamide), have been successfully constructed under solvothermal conditions. The structures of two complexes have been successfully determined by single crystal X-ray diffraction (CIF files CCDC nos. 1852377 (I) and 1852378 (II)). In addition, in vitro antitumor activity of compounds I and II on four human kidney cancer cells (GRC-1, A-498, ACHN and 786-P) was further determined and the results show that the two compounds showed promising activity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CANCER cells
*COORDINATION polymers
*X-ray diffraction
*RENAL cancer
*POLYMERS
Subjects
Details
- Language :
- English
- ISSN :
- 10703284
- Volume :
- 44
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Russian Journal of Coordination Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 134171199
- Full Text :
- https://doi.org/10.1134/S1070328419010044