Back to Search
Start Over
Didehydroisobenzofuran: A New Reactive Intermediate for Construction of Isoacenofuran.
- Source :
-
Chemistry - A European Journal . 12/17/2018, Vol. 24 Issue 71, p18886-18889. 4p. - Publication Year :
- 2018
-
Abstract
- An efficient generation method of didehydroisobenzofuran, a new heteroaryne species, was developed by bromine/lithium exchange of the dibromoisobenzofuran. The reactive intermediate, thus generated, was trapped by appropriate arynophile to give the [2+2], [2+3], and [2+4] cycloadducts, respectively. Moreover, the reaction could be applied to the syntheses of isoanthracenofurans (anthra[2,3‐c]furans), a new class of heteroacenes, with isoelectoronic structure to the corresponding acenoheteroles (anthra[2,3‐b]furans). An efficient generation method of didehydroisobenzofuran, a new heteroaryne species, was developed by bromine/lithium exchange of the dibromoisobenzofuran. The reactive intermediate, thus generated, was trapped by arynophiles to give various cycloadducts, one of which could be converted to isoanthracenofurans, a new class of heteroacenes, possessing unique physical properties (see scheme). [ABSTRACT FROM AUTHOR]
- Subjects :
- *ISOBENZOFURAN
*BIOCONJUGATES
*ACENES
*BROMINE
*LITHIUM
Subjects
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 24
- Issue :
- 71
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 133628846
- Full Text :
- https://doi.org/10.1002/chem.201804655