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Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation.

Authors :
Rhie, Suhn K.
Schreiner, Shannon
Witt, Heather
Lay, Fides D.
Yu Guo
Farnham, Peggy J.
Armoskus, Chris
Camarena, Adrian
Spitsyna, Valeria N.
Berman, Benjamin P.
Evgrafov, Oleg V.
Knowles, James A.
Source :
Science Advances. Dec2018, Vol. 4 Issue 12, p1-15. 15p.
Publication Year :
2018

Abstract

The article discusses the research on three-dimensional epigenomic mapping of olfactory neuronal cells from neuroepithelium to analysis genetic regulation. Topics discussed include chromatin interaction and topologically associating domain, the culture of neuroepithelial cells taken from nasal biopsy and conducting gene expression profile to predict gene interaction.

Details

Language :
English
ISSN :
23752548
Volume :
4
Issue :
12
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
133591851
Full Text :
https://doi.org/10.1126/sciadv.aav8550