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Yolk sac-embryo distance in correlation with soluble form of vascular endothelial growth factor levels in pregnancy with potentially reserved evolutivity.
- Source :
-
Medical Ultrasonography . Dec2018, Vol. 20 Issue 4, p487-492. 6p. - Publication Year :
- 2018
-
Abstract
- <bold>Aims: </bold>Embryonic demise is a frequent complication of the first trimester pregnancy. The purpose of this study was to evaluate the correlation between a serum biomarker, the soluble form of the vasculo-endothelial growth factor (sFlt-1) and the distance between the yolk sac (YS) and embryo (DYSE), determined by ultrasonography.<bold>Material and Methods: </bold>The study was a prospective case-control study that included 2 groups of patients - the control group with 81 first-trimester pregnancies in evolution and the case group with 89 first-trimester pregnancies with a potentially reserved evolutivity.<bold>Results: </bold>A correlation between the serum level of sFlt-1 and DYSE in embryos with crown-rump length (CRL) greater than 5 mm was identified, showing that a DYSE ≤3 mm correlates with a low level of sFlt-1 (p<0.05) and a DYSE> 4 mm correlates with an increased level of sFlt-1 (p<0.05).<bold>Conclusions: </bold>A low level of sFlt-1 associated with a distance between the embryo and yolk sac of small dimensions, respectively <3 mm, correlates with an increased rate of non-viable embryos. This correlation between an ultrasound and a serum parameter is of great value and brings important information about the viability of firsttrimester pregnancies. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18444172
- Volume :
- 20
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Medical Ultrasonography
- Publication Type :
- Academic Journal
- Accession number :
- 133502368
- Full Text :
- https://doi.org/10.11152/mu-1504