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Clinical performance of a dedicated self-apposing stent for the treatment of left main stem disease. Results of the left Main AngioplasTy wIth a Self-apposing StEnt - the MATISSE study.
- Source :
-
Cardiovascular Revascularization Medicine . Oct2018:Part B, Vol. 19 Issue 7, p831-836. 6p. - Publication Year :
- 2018
-
Abstract
- <bold>Background: </bold>In the recent years percutaneous treatment of the left main stem (LM) has gained a precise role as a result of consistent scientific evidence vs. coronary artery bypass. A self-apposing stent offers an improved adaptation to the vessel wall, especially in case of tapered vessels; aim of this study was to investigate the role of a novel self-apposing, sirolimus-eluting stent (Stentys, France) for the treatment of LM coronary artery disease.<bold>Methods and Results: </bold>MATISSE is a retrospective, multicenter registry, which enrolled 151 patients treated with the device at 17 international centers. Primary study endpoint was the occurrence of major adverse cardiovascular events (MACE), a composite endpoint of cardiac death, target lesion revascularization (TLR) and target-vessel myocardial infarction, at 9months clinical follow-up. Secondary endpoints included procedural success, the single determinants of MACE and stent thrombosis. Lesions were located in distal LM bifurcation in 84% of the patients. Procedural success was achieved in 150 patients. The average follow-up length was 348±52days. MACE occurred in 14 (9.3%) patients with 2 (1.3%) cardiac deaths. TLR occurred in 8 patients (5.3%). There were 2 cases of definite stent thrombosis, 1 acute and 1 very late.<bold>Conclusions: </bold>A self-apposing stent, when used for LM PCI in a real world, high risk population, showed good immediate procedural results with low rates of adverse events at mid-term follow-up. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15538389
- Volume :
- 19
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Cardiovascular Revascularization Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 133393156
- Full Text :
- https://doi.org/10.1016/j.carrev.2018.03.005