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Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial.
- Source :
-
Clinical Rehabilitation . Dec2018, Vol. 32 Issue 12, p1666-1675. 10p. 1 Diagram, 3 Charts. - Publication Year :
- 2018
-
Abstract
- Objective: To evaluate the effectiveness of acupuncture for pain relief and function improvement in patients with knee osteoarthritis and to determine the feasibility of an eight-week acupuncture intervention. Design: Pilot randomized controlled trial. Setting: Three teaching hospitals in China. Subjects: Patients with knee osteoarthritis (Kellgren grade II or III). Interventions: Patients were randomly assigned to an eight-week (three sessions per week) intervention of either traditional Chinese acupuncture or sham acupuncture. Main measures: The primary outcome was response rate—the proportion of patients achieving score ⩾36% decrease in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and function at week 8 compared with baseline. Secondary outcomes included pain, function and quality of life. Results: Of 42 patients randomized, 36 (85.7%) completed the study. There was no significant difference in response rate between the traditional Chinese acupuncture and control groups: 61.9% (13 of 21) versus 42.9% (9 of 21) achieved score ⩾36% decrease in WOMAC pain and function at week 8 (P = 0.217). The sum of WOMAC pain and function scores at week 8 was 11.6 (9.1) in the traditional Chinese acupuncture group compared with 16.3 (10.9) in the control group (P = 0.183). There was no significant difference between groups. Three adverse events were recorded and were classified as mild. Conclusion: It showed that three sessions per week acupuncture intervention of knee osteoarthritis was feasible and safe. No difference was observed between groups due to small sample size. Larger (sample size ⩾ 296) randomized controlled trials of this intervention appear justified. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OSTEOARTHRITIS treatment
*KNEE diseases
*ACADEMIC medical centers
*ACUPUNCTURE
*ACUPUNCTURE points
*CHI-squared test
*STATISTICAL correlation
*LIFE skills
*CHINESE medicine
*PAIN
*QUALITY of life
*QUESTIONNAIRES
*RESEARCH funding
*STATISTICAL sampling
*T-test (Statistics)
*PILOT projects
*RANDOMIZED controlled trials
*TREATMENT effectiveness
*DATA analysis software
*DESCRIPTIVE statistics
*MANN Whitney U Test
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 02692155
- Volume :
- 32
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Clinical Rehabilitation
- Publication Type :
- Academic Journal
- Accession number :
- 133291968
- Full Text :
- https://doi.org/10.1177/0269215518790632