Online 32-channel signal processing and integrated database improve navigation during cranial stereotactic surgeries

Target point accuracy is a main issue in functional stereotactic procedures for the implantation of deep brain stimulators. Next to standard stereotactic methods, intraoperative microelectrode recordings help to reach the target point. While currently up to 5 electrodes are used, we introduce a new 32-channel system. Our probes allow for recording 32 neural signals alongside up to 1 cm of the planned trajectory simultaneously. The signal evaluation is supported by customized analysis and visualization tools contained in our navEgate DAQ software. The acquisition software has access to the navEbase database that holds characteristic signal features with respect to their anatomic origin. Currently recorded signals can be compared against nominal values from the database. While preclinical studies of our system are on the way, we are convinced that the possibility to record neural depth profiles will fasten intrapoerative microelectrode recordings, and that the feedback from navEbase will assist teams in questionable cases. [Copyright &y& Elsevier]