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Magee Equation Recurrence Score Is Associated With Distal Metastatic Risk in Male Breast CarcinomasExperience From Two Institutions.
Magee Equation Recurrence Score Is Associated With Distal Metastatic Risk in Male Breast CarcinomasExperience From Two Institutions.
- Source :
-
American Journal of Clinical Pathology . Dec2018, Vol. 150 Issue 6, p491-498. 8p. 2 Color Photographs, 5 Charts. - Publication Year :
- 2018
-
Abstract
- Objectives To conduct a clinicopathologic study of male breast carcinoma with Magee equation recurrence score (RS). Methods Seventy-four cases of male invasive breast cancers (MBCs) were studied, including 63 hormone receptor (HR)-positive, 10 human epidermal growth factor receptor 2-positive, and one triple-negative breast cancers. Results Among 63 HR-positive MBC patients, nine patients developed distal metastasis. Statistical analysis demonstrated distal metastasis was significantly associated with positive lymph node, high Nottingham grade, and increased Magee equation RS. All HR-positive MBCs were further stratified into two categories (low RS <18; intermediate/high RS ≥18). There was a significantly increased risk for distal metastasis in MBCs with intermediate/high Magee equation RS, but no increased risk for lymph node metastasis. Conclusions Our data suggest Magee equation RS may be useful to predict distal metastatic risk in MBC patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- *METASTATIC breast cancer
*CANCER relapse
*EPIDERMAL growth factor receptors
Subjects
Details
- Language :
- English
- ISSN :
- 00029173
- Volume :
- 150
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- American Journal of Clinical Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 133211677
- Full Text :
- https://doi.org/10.1093/ajcp/aqy078