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Antibacterial activity of reduced iron clay against pathogenic bacteria associated with wound infections.
- Source :
-
International Journal of Antimicrobial Agents . Nov2018, Vol. 52 Issue 5, p692-696. 5p. - Publication Year :
- 2018
-
Abstract
- HIGHLIGHTS • OMT Blue Clay kills human pathogens existing in free-floating and adherent states. • Clay suspension is more bioactive than the solution of clay's metal derivatives. • Species differences in past, present results allude to impact of strain variation. Abstract Clay is a substance historically utilized by indigenous cultures for the treatment of superficial wound infections. This study evaluated the effects of a recently identified clay – OMT Blue Clay – against staphylococci, streptococci, Enterobacteriaceae and non-fermenting Gram-negative bacilli. The clay and its aqueous leachate were evaluated against the bacteria in biofilm and planktonic states. Time-kill studies were used to assess planktonic activity. Biofilms on medical-grade Teflon discs were treated with a hydrated clay suspension or leachate. For the planktonic studies, clay and leachate exhibited bactericidal activity against all strains tested, with the exception of leachate against Staphylococcus aureus IDRL-6169 and USA300. All strains treated with clay suspension and leachate resulted in statistically significant biofilm population reductions compared with controls, except S. aureus IDRL-6169 and USA300 (P ≤ 0.05). OMT Blue Clay and its aqueous leachate exhibited bactericidal activity against a range of human pathogens in the planktonic and biofilm states. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09248579
- Volume :
- 52
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- International Journal of Antimicrobial Agents
- Publication Type :
- Academic Journal
- Accession number :
- 132896736
- Full Text :
- https://doi.org/10.1016/j.ijantimicag.2018.07.018