A new route for the synthesis of functionalized benzothiadiazine 1,1-dioxide derivatives via intramolecular C-H activation reactions of N,N′,N′′-trisubstituted guanidines and benzenesulfonylchloride.

In this study, a simple and appropriate procedure for the synthesis of functionalized benzothiadiazine 1,1-dioxide with good yields via the Cu-catalyzed intramolecular C-H activation reaction from benzenesulfonylchloride and N,N′,N′′-trisubstitutedguanidines, generated by copper(II) oxide-catalyzed hydroamination of carbodiimides, is reported. [ABSTRACT FROM AUTHOR]