The Gbetagamma sensitivity of a P13K is dependent upon a tightly associated adaptor, p101.

Authors :: Stephens, L.R.
Eguinoa, A.
Erdjument-Bromage, H.
Lui, M.
Cooke, F.
Coadwell, J.
Smrcka, A. S.
Thelen, M.
Cadwallader, K.
Tempst, P.
Hawkins, P. T.
Source :: Cell. 04/04/97, Vol. 89 Issue 1, p105. 10p. 6 Diagrams, 4 Graphs.
Publication Year :: 1997
Abstract: Studies protein kinases which stimulates accumulation of phosphatidylinositol trisphosphate in their target cells. Known regulatory adaptors; Utilization of several overlapping fragments derived from cDNA libraries; Description in platelets of a Gbeta gamma-sensitive P13K activity as recognizable by a delta p85 antibodies.

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