肾脏肿瘤患者CT灌注参数与肾功能生化检测指标的相关性研究.

Objective: To investigate the correlation between CT perfusion parameters and renal function biochemical indexes in patients with renal tumor. Methods: 35 patients with renal tumor ine from March 2013 to January 2018 were selected as the observation group,another 35 healthy persons who were admitted to The Sixth People's Hospital of Hebei Province during the same period were selected as control group. CT perfusion imaging was performed in two groups, and CT perfusion parameters such as equivalent blood volume (Equiv BV), permeability surface (Ps), blood flow (BF) were obtained. The renal function biochemical indexes such as blood urea nitrogen (BUN), serum creatinine (Scr), total cholesterol (TC) and triglyceride (TG) were detected in two groups, and the results of the above indexs in two groups were compared. The correlation between CT perfusion parameters and renal function biochemical indexes was analyzed by Pearson correlation analysis. Results: Compared with the control group, the CT perfusion parameters such as Equiv BV,Ps and BF in the observation group were all decreased, and the levels of renal function biochemical indexes such as BUN, Scr, TC and TG were all increased, the differences were statistically significant (P<0.05). Pearson correlation analysis showed that CT perfusion parameters such as Equiv BV, Ps and BF were negatively correlated with renal function biochemical indexes TC and BUN (P< 0.05), but not correlated with Scr and TG (P>0.05). Conclusion: CT perfusion parameters such as Equiv BV, Ps and BF of renal tumor patients were lower, and the levels of BUN, Scr, TC and TG were higher. CT perfusion parameters are negatively correlated with the levels of BUN and TG, which can be used as an auxiliary method to evaluate renal function in patients with renal tumor. [ABSTRACT FROM AUTHOR]